Dr. Timir Tripathi

Molecular and Structural Biophysics Laboratory

Current Research

Research interest: Structure-function-folding-flexibility-dynamics relationship of proteins using biochemistry, molecular biology, biophysics, and computational approaches. 

Our laboratory is working on three broad areas:

 

  1. The characterization of enzymes of chemotherapeutic importance for structure based drug development. We target two major protein systems: 1) Thiol-based redox-active proteins, and 2) Aminoacyl tRNA-synthetases.
  2. Understanding mRNA export by studying the novel interacting partners of mRNA export factor, Mex67 in yeast.
  3. Inhibition of β-amyloid fibrillation using plasmapheresis, where we target Transferrin.